Peter hace un cómic polémico llamado "Por Dios, Peter", contando con un gran éxito al principio sin embargo, causa controversia al publicar una tira sexista, la cual irrita a las mujeres locales, por lo que consiguen expulsar a la familia Griffin de Quahog. Cuando se detienen en una gasolinera, su auto es robado, dejándolos varados fuera de Springfield. En el Kwik-E-Mart, Homer Simpson presenta a los Griffin y los lleva al Departamento de Policía de Springfield, donde son rechazados por el jefe Wiggum. La familia Simpson pone a la familia Griffin en su casa hasta que las cosas mejoren. Bart Simpson conoce a Stewie y le enseña a patinar. Cuando Bart es intimidado por Nelson Muntz, Stewie se venga al secuestrar y torturar a Nelson. Mientras tanto, Lisa trata de encontrar un talento poseído por Meg. Cuando ella descubre que Meg es buena en el saxofón, le resta importancia al talento por celos. Chris y Brian sacan adar una vuelta al perro de los Simpson, Ayudante de Santa. Brian trata de enseñar la independencia del pequeño ayudante de Santa, pero este último se escapa cuando está libre. Marge se da cuenta de Ayudante de Santa no aparece, y Chris y Brian fingem su presencia hasta que finalmente regresa. Homer y Peter tratan distintos planes para encontrar el coche de Peter, cada una ignición prematura, hasta que descubren que Hans Moleman fue el que se llevó el automóvil.

Peter is hired to read Joe's new children's book; Brian takes up running to impress a girl.

Peter and Lois open a bakery, but things get out of hand when Peter comes up with a way to attract customers.

After getting a cosmetic surgery, Brian becomes a real estate agent, only to get in trouble with Quagmire.

On the night before Thanksgiving, Peter and Brian get drunk and eat the whole turkey, so they have to get a new one on Thanksgiving Day. With Peter gone, Stewie tries to help Chris take over as the man of the house.

Peter and the guys set out to throw Jesus the best birthday party in order to help him lose his virginity.

Stewie and Brian take Chris back through time to help him with history class, only to end up stuck in the past.

Brian begins to think he's not so smart when he takes the SAT'S for Meg and gets a low score, so Peter decides to show him the joys of being an idiot.

Meg becomes a foot-fetish model; Brian accompanies Stewie on an adventure outside of preschool.

Quagmire faces charges of statutory rape, and during his trial, his mom makes a surprise appearance to explain why he is the way that he is.

Peter and the guys start a detective agency and discover that Chris is a thief. In the meantime, Lois is worried about Chris when gets involved in a delusional relationship.

Stewie impregnates himself with Brian's DNA to save their friendship, while Peter and the guys try to make a viral video.

Cleveland becomes an unlicensed therapist and gives Lois marriage advice that Peter does not like, and Quagmire gets Meg a job working in airport security.

Joe decides to embrace life by taking the guys on a road trip to Niagra Falls, where he makes an unexpected decision.

Después de asistir a la escuela de obediencia, Brian se vuelve mucho más sumiso. Eso hace que Peter extrañe la versión combativa de su amigo. Mientras, Chris se siente traicionado cuando descubre que su nuevo amigo lo usó para acercarse a Meg.

When Peter's insulted by old friends at a roasting of him, he joins a group of mean girls.

Peter prepares for a fight with Liam Neeson, while Lois becomes a class mom and pays more attention to the other children over Stewie.

Lois books a couple's vacation, but it turns out to be a marriage counseling program. Carter is frustrated because the kids are so into their electronics.

Sin Resumen